个人基本情况：
姓名： 生威
性别： 女
出生年月： 1980年02月
民族： 汉族
政治面貌： 中共党员
职称职务： 研究员，博士研究生导师
教育经历：
2003.09-2008.06 中国农业大学，资源与环境学院，硕博连读，博士
1998.09-2002.07 东北农业大学，资源与环境学院，本科
主要工作经历：
2018.12-至今 天津科技大学 食品科学与工程学院 研究员
2012.11-2018.11 天津科技大学 食品科学与工程学院 副研究员
2011.04-2012.10 天津科技大学 食品工程与生物技术学院 助理研究员
2008.09-2011.04 天津科技大学 食品科学与工程博士后流动站 博士后
从事研究的学科专业领域：
1. 食品科学
2. 食品质量与安全
主要研究方向：
1. 食品中小分子危害物及致病微生物多克隆抗体、单克隆抗体、纳米抗体、基因工程抗体制备
2. 食品危害物的酶免疫分析检测技术研究
3. 基于新型纳米探针和分子探针的食品安全快速检测新技术研究
4. 食品安全ELISA试剂盒、胶体金试纸条、荧光速测卡等快检产品开发
招收研究生学科及方向：
1. 招收博士研究生
(1) 食品科学与工程
2. 招收硕士研究生
(1) 食品科学与工程
(2) 公共卫生与预防医学
(3) 生物与医药
(4) 食品加工与安全
教授课程：
《食品安全与卫生学B》，本科
《食品安全专题讲座》，本科
《食品质量前沿探究》， 本科
主要科研项目：
1.食品中蛋白质源生物胺选择性识别材料和传感检测新技术研发 (No.2016YFD0401204-04, 113.9万元)，“十三五”国家重点研发计划项目子课题，主持
2.基于量子点标记的邻苯二甲酸酯类污染物可视化免疫检测研究(No.31201353, 23万元)，国家自然科学基金(青年)，主持
3.海洋食品加工过程药物残留检测控制技术研究(No.2012BAD28B05-05, 40万元)，“十二五”国家科技支撑计划项目子课题，主持
4.食品加工过程生物有害物控制技术工艺参数优化(No.2012AA101604-03, 180万元)，国家863项目子课题，主持
5.食品质量安全控制关键技术研发及应用平台建设(No.16PTSYJC00130, 40万元)，天津市科技计划项目，主持
6.基于量子点标记的恩诺沙星可视化免疫检测技术研究 (No.13JCQNJC15300, 6万元)，天津市应用基础与前沿技术研究计划(自然科学基金青年项目)，主持
7.基于上转换纳米材料构建高灵敏免疫传感检测方法检测食品中典型环境激素(No.SKLFNS-KF-201819, 6万元)，省部共建食品营养与安全国家重点实验室开放课题，主持
8.基于上转换纳米材料的违禁兽药高灵敏荧光免疫传感检测新方法研究(gxb201904，2万元)，食品企业质量安全检测技术示范中心开放课题基金，主持
9.2013年天津市高校“优秀青年教师资助计划”(3万元)，主持
10.横向项目：农药残留快速检测试剂盒研发，主持
11.横向项目：真菌毒素单克隆抗体和抗原材料开发，主持
12.横向项目：黄曲霉毒素AFB1抗原材料开发，主持
科研论文：
近年来，在Trends in Food Science & Technology (IF:17.4, 1区 Top Journal)，Chemical Engineering Journal (IF:12.5, 1区 Top Journal)，Journal of Hazardous Materials (IF:10.6, 1区 Top Journal)，Food Chemistry (IF:10.4, 1区 Top Journal)，Sensors and Actuators B: Chemical (IF:8.3, 1区 Top Journal)，Journal of Agricultural and Food Chemistry (IF: 6.7, 1区 Top Journal)，Food Control (IF: 7.0, 1区 Top Journal)等期刊上以第一作者或通讯作者发表SCI论文40余篇。
1. Ziwuzhen Wang, Zixin Jin, Hongyu Shi, Zhiwei Liu, Yuqing Yang, Nawei Shi, Wanlin Jia, Meichao Zhang, Shuo Wang, Wei Sheng*. S/N induced coordination isomerism hydrogels on 3D-printed device for machine learning-assisted multiplex detection of heavy metal ions. Chemical Engineering Journal. 2026, 537, 176278.
2. Zixin Jin, Yuqing Yang, Hongyu Shi, Zhiwei Liu, Dongmei Bai, Ziwuzhen Wang, Caixu Fan, Yamin Liu, Qiuyue Ji, Wei Sheng*, Shuo Wang*. Preparation of acetamiprid monoclonal antibody and its application in colorimetric and photothermal dual-mode immunochromatographic assay based on Cu-doped PDA composite. Food Chemistry. 2026, 498, 147166.
3. Zixin Jin, Zhiwei Liu, Ziwuzhen Wang, Yuqing Yang, Hongyu Shi, Caixu Fan, Yamin Liu, Qiuyue Ji, Wei Sheng*, Long Ma*, Shuo Wang*. Real-time food freshness monitoring with AI assisted colorimetric and fluorescent dual-mode paper-based sensors: Harnessing size-dependent effects of mesoporous Cu2O. Chemical Engineering Journal. 2025, 526, 170581.
4.Ziwuzhen Wang, Wei Sheng*, Zixin Jin, Hongyu Shi, Zhiwei Liu, Yuqing Yang, Shuo Wang,*, Qiuyue Ji, Caixu Fan, Yamin Liu. Dual network CMCS/PNIPAM temperature-sensitive hydrogel based fluorescent and RGB colorimetric dual-mode immunosensor for detection of capsaicinoids as an exogenous index in edible oil samples. Chemical Engineering Journal. 2025,521,166601.
5.Wei Sheng*, Xinshuang Tang, Tingting Ya, Qiuyue Ji, Zixin Jin, Lishuai Ren, Ziwuzhen Wang, Shuo Wang*, Caixu Fan, Yamin Liu. Multi-model immunochromatographic assay based on “three in one” Fe3O4@PDA@Pt nanocomposite for ultrasensitive detection of zearalenone in cereals. Food Chemistry. 2025, 482, 144185.
6.Ziwuzhen Wang, Wei Sheng*, Xinshuang Tang, Tingting Ya, Zixin Jin, Shuo Wang*, Qiuyue Ji, Caixu Fan, Yamin Liu. Temperature-sensitive driving assembled fluorescence hydrogel based dual-mode sensor for adsorbing and detecting of heavy metal cadmium ions in food and water. Food Chemistry. 2025,470, 142727.
7.Zixin Jin, Wei Sheng*, Ziwuzhen Wang, Xinshuang Tang, Tingting Ya, Shuo Wang*, Qiuyue Ji, Caixu Fan, Yamin Liu. Homogeneous fluorescence immunoassay based on AuNPs (AgNPs) quenching multicolor QDs@hydrogel beads for the simultaneous ultra-sensitive determination of aflatoxin B1 and capsaicinoids in food. Food Chemistry. 2025, 464, 141570.
8.Na Huang，Wei Sheng*，Dongmei Bai，Meiyi Sun，Lishuai Ren，Shuo Wang，Zixin Jin. Multiplex fluorescence quenching immunoassay based on multicolor magnetic quantum dot and dual spectral-overlapped polydopamine nanospheres for ultrasensitive detection of aflatoxin B1, zearalenone, ochratoxin A, and fumonisin B1. Sensors and Actuators: B. Chemical. 2024, 414, 135968.
9. Wei Sheng*, Meiyi Sun, Dongmei Bai, Lishuai Ren, Tingting Ya, Zixin Jin, Shuo Wang, Ziwuzhen Wang, Xinshuang Tang. Colorimetric and photothermal double-model immunochromatographic assay based on MoS2@Au nanocomposite for high sensitive detection of imidacloprid in food. Microchemical Journal. 2024,201,110637.
10. Zixin Jin, Wei Sheng*, Meiyi Sun, Dongmei Bai, Lishuai Ren, Shuo Wang*, Ziwuzhen Wang, Xinshuang Tang, Tingting Ya. Preparation of a capsaicinoids broad spectrum antibody and its application in non-enzyme immunoassay based on DMSNs@PDA@Pt. Journal of Hazardous Materials. 2024,466,133670.
11. Zixin Jin, Wei Sheng*, Lishuai Ren, Dongmei Bai, Meiyi Sun, Shuo Wang*, Tingting Ya, Xinshuang Tang, Ziwuzhen Wang. Homogeneous fluorescence immunoassay based on AuNPs quenching dendritic silica assembled with multicolor QDs for the simultaneous determination of four mycotoxins in cereals. Chemical Engineering Journal. 2024,480,148247.
12. Na Huang, Wei Sheng*, Zixin Jin, Dongmei Bai, Meiyi Sun, Lishuai Ren, Shuo Wang, Ziwuzhen Wang, Xinshuang Tang, Tingting Ya. Colorimetric and photothermal dual-mode immunosensor based on Ti3C2Tx/AuNPs nanocomposite with enhanced peroxidase-like activity for ultrasensitive detection of zearalenone in cereals. Microchimica Acta. 2023,190,479.
13. Zixin Jin, Wei Sheng*, Na Huang, Lishuai Ren, Meiyi Sun, Dongmei Bai, Shuo Wang, Ziwuzhen Wang, Xinshuang Tang, Tingting Ya. Blue-green-red multicolor upconversion nanoparticles based fluorescence immunoassay for simultaneous detection of three mycotoxins in cereals. Microchemical Journal. 2023, 193, 109181.
14. Zixin Jin, Wenjing Jia, Wei Sheng*, Meiyi Sun, Lishuai Ren, Dongmei Bai, Shuo Wang, Tingting Ya, Ziwuzhen Wang, Xinshuang Tang. Fluorescence immunoassay for simultaneous detection typical β-agonists in animal derived food using blue-green upconversion nanoparticles as labels. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. 2023, 303,123253.
15. Xiaoxiao Lin, Zhiguang Wang, Xuexia Jia, Ruipeng Chen, Yingkai Qin, Yalan Bian, Wei Sheng*, Shuang Li*, Zhixian Gao*. Stimulus-responsive hydrogels: A potent tool for biosensing in food safety. Trends in Food Science & Technology. 2023, 131,91-103.
16. Zixin Jin, Wei Sheng*, Junli Liu, Chenchen Liu, Yueru Ma, Shuo Wang, Wanli Zhang, Na Huang. A fluorescence immunoassay based on GSH destroying MnO2@QDs for the simultaneous ultrasensitive detection of four mycotoxins in cereals. Food Chemistry. 2023,420,136099.
17. Na Huang, Wei Sheng*, Dongmei Bai, Meiyi Sun, Lishuai Ren, Shuo Wang*, Wanli Zhang, Zixin Jin. Multiplex bio-barcode based fluorometric immunoassay for simultaneous determination of zearalenone, fumonisin B1, ochratoxin A, and aflatoxin B1 in cereals. Food Control.2023,150,109759.
18. Wei Sheng*, Jing Guo, Chenchen Liu, Yueru Ma, Junli Liu, Haoyu Zhang. Quantitative determination of four mycotoxins in cereal by fluorescent microsphere based immunochromatographic assay. Journal of the Science of Food and Agriculture.2023,103(8):4017-4024.
19. Wanli Zhang, Wei Sheng*, Haoyu Zhang, Zixin Jin, Biao Zhang, Na Huang, Shuo Wang*. Freeze-synthesized bio-barcode immunoprobe based multiplex fluorescence immunosensor for simultaneous determination of four nitrofuran metabolites. Food Chemistry. 2022, 393, 133424.
20. Xufang Huang, Wei Sheng*, Haonan Chen, Biao Zhang, Na Huang, Shuo Wang*. Upconversion nanoparticles-based fluorescence immunoassay for the sensitive detection of 2-amino-3-methylimidazo [4, 5-f] quinoline (IQ) in heat processed meat. Sensors. 2022,22,8.
21. Biao Zhang, Cong Li, Wenjing Jia, Wanli Zhang, Na Huang, Wei Sheng*, Shuo Wang*. A broad-spectrum antibody based bio-barcode fluorescence immunosensor for simultaneous detection of eight heterocyclic aromatic amines (HAAs) in heat processed meat. Sensors and Actuators: B. Chemical. 2021, 337, 129759.
22.Wei Sheng*, Biao Zhang, Qiuxia Zhao, Shuo Wang*, Yan Zhang. Preparation of a broad-Spectrum heterocyclic aromatic amines (HAAs) antibody and its application in detection of eight HAAs in heat processed meat. Journal of Agricultural and Food Chemistry. 2020, 68, 15501−15508.
23. Wei Sheng*, Na Huang, Yue Liu, Biao Zhang, Wanli Zhang, Shuo Wang*. An ultrasensitive fluorescence immunoassay based on magnetic separation and upconversion nanoparticles as labels for the detection of chloramphenicol in animal-derived foods. Food Analytical Methods.2020, 13(11):2039-2049.
24. Biao Zhang, Wei Sheng*, Yue Liu, Na Huang, Wanli Zhang, Shuo Wang*. Multiplexed fluorescence immunoassay combined with magnetic separation using upconversion nanoparticles as multicolor labels for the simultaneous detection of tyramine and histamine in food samples. Analytica Chimica Acta, 2020, 1130: 117-125.
25. Wei Sheng*, Yingjie Shi, Jie Ma, Lulu Wang, Biao Zhang, Qing Chang, Wenxia Duan, Shuo Wang*. Highly sensitive atrazine fluorescence immunoassay by using magnetic separation and upconversion nanoparticles as labels. Microchimica Acta. 2019, 186(8):564.
26. Wei Sheng*, Wenxia Duan, Yingjie Shi, Qing Chang, Yan Zhang, Yang Lu, Shuo Wang*. Sensitive detection of bisphenol A in drinking water and river water using an upconversion nanoparticles-based fluorescence immunoassay in combination with magnetic separation. Analytical Methods.2018,10(44):5313-5320.
27.Wei Sheng*, Qing Chang, Yingjie Shi, Wenxia Duan, Yan Zhang, Shuo Wang*. Visual and fluorometric lateral flow immunoassay combined with a dual-functional test mode for rapid determination of tetracycline antibiotics. Microchimica Acta. 2018, 185(9):404.
28.Wei Sheng*, Hesen Wu, Weihong Ji, Zhi Li, Fangyu Chu, Shuo Wang*. Visual non-instrumental on-site detection of fumonisin B1, B2, and B3 in cereal samples using a clean-up combined with gel-based immunoaffinity test column assay. Toxins. 2018, 10(4):165.
29. Wei Sheng*, Yue Liu, Shijie Li, Yang Lu, Qing Chang, Yan Zhang, Shuo Wang*. Lateral flow quantum-dot-based immunochromatographic assay and fluorescence quenching immunochromatographic assay with quantum dots as fluorescence donors to visually detect bisphenol A in food and water samples. Food Analytical Methods. 2018,11(3):675-685.
30. Wei Sheng*, Shijie Li, Yue Liu, Junping Wang, Yan Zhang, Shuo Wang*. Visual and rapid lateral flow immunochromatographic assay for enrofloxacin using dyed polymer microspheres and quantum dots. Microchimica Acta. 2017,184(11):4313-4321.
31. Wei Sheng, Congcong Sun, Guozhen Fang, Xuening Wu, Gaoshuang Hu, Yan Zhang, Shuo Wang*. Development of an enzyme-linked immunosorbent assay for the detection of tyramine as an index of freshness in meat and seafood. Journal of Agricultural and Food Chemistry. 2016,64(46):8944-8949.
32. Wei Sheng, Xuqin Ran, Gaoshuang Hu, Yan Zhang, Yang Lu, Bing Liu, Shuo Wang*. Development of an enzyme-linked immunosorbent assay for the detection of 2-amino-3-methylimidazo [4, 5-f] quinoline (IQ) in processed foods. Food Analytical Methods. 2016,9(4):1036-1045.
33. Wei Sheng, Li Yang, Junping Wang, Yan Zhang, Shuo Wang*. Development of an enzyme-linked immunosorbent assay for the detection of gentamycin residues in animal-derived foods. LWT—Food Science and Technology. 2013,50(1):204-209.
34. Wei Sheng, Yuanzhen Li, Xin Xu, Meng Yuan, Shuo Wang*. Enzyme-linked immunosorbent assay and colloidal gold-based immunochromatographic assay for several (fluoro)quinolones in milk. Microchimica Acta. 2011,173(3-4):307-316.
35. Wei Sheng, Xunfeng Xia, Keyi Wei, Ji Li, Qing X. Li, Ting Xu*. Determination of marbofloxacin residues in beef and pork with an enzyme-linked immunosorbent assay. Journal of Agricultural and Food Chemistry. 2009, 57(13):5971-5975.
36. Wei Sheng, Ting Xu, Hui X. Ma, Xin T. Wang, Qing X. Li, Ji Li*. Development of an indirect competitive enzyme-linked immunosorbent assay for detection of danofloxacin residues in beef, chicken and pork meats. Food and Agricultural Immunology. 2009, 20(1):35-47.
37.蔺晓晓，生威*，高志贤*. 基于Al3+与ATP协同增敏荧光法快速检测牛奶中氧氟沙星[J].食品安全质量检测学报. 2023, 14(6):40-46.
38. 张彪，黄娜，张万利，王硕，生威*. 基于上转换纳米材料与磁分离的荧光免疫分析方法检测食品中酪胺[J]. 食品科学. 2021, 42(14):270-275.
39. 吴 烁，张 彪，张万利，邵静梅，刘飘雪，生威*. 荧光微球免疫层析方法定量检测水产品中4种硝基呋喃代谢物[J]. 食品科学. 2021, 42(20):299-304.
40. 赵秋霞，生威*，王璐璐，尚淑娜，张燕，王硕. 一种检测杂环胺类化合物的酶联免疫检测方法的建立[J]. 食品工业科技. 2019,40(21):58-64.
41. 沙志聪，其木格，贾增艳，张燕，生威*. 量子点标记免疫层析试纸条快速检测谷物中赭曲霉毒素A[J]. 食品工业科技. 2019,40(17):191-195,190.
42. 生威，吴雪宁，李诗洁，朱冰，王俊平，张燕，王硕*. 呋喃它酮代谢物可视化凝胶柱快速免疫检测方法研究[J]. 现代食品科技. 2017, 33(5):277-281, 318.
43. 生威，吴雪宁，胡高爽，李诗洁，刘越，张燕，王硕*. 恩诺沙星可视化凝胶柱快速免疫检测方法研究[J]. 食品研究与开发. 2016,37(19):114-117.
44. 生威，那宇，张琳，刘冰，王硕*. 胶体金免疫层析试纸条快速检测水和玉米中阿特拉津的残留[J]. 现代食品科技.2012, 28(3):360-363.
45. 生威，李季，许艇*. 动物性产品中硝基呋喃类抗生素残留检测方法研究进展[J]. 农业环境科学学报，2006,25: 429-434.
著作及教材编写：
1. 《食品安全性评价综合实验》，中国林业出版社，2014.02. 参编
2. 《食品生物技术》，科学出版社，2013.11. 参编
授权专利：
1．生威，张彪，王硕. 一种同时检测酪胺和组胺的荧光免疫方法，ZL202010056556.8.
2. 生威，王硕，赵秋霞，张燕. 一种杂环胺8-MeIQx 半抗原、抗体及其制备方法和应用, ZL201910445688.7.
3. 王俊平，生威，张昕哲，王硕，张燕. 烯啶虫胺半抗原、人工抗原和抗体及其制备方法与应用，ZL201210429862.7.
4. 刘冰，童贝，生威，张燕，王硕. 一种同时检测沙丁胺醇和氟甲喹的免疫层析试纸条及其制备方法，ZL201610257516.3.
5. 张燕，刘冰，生威，王硕.一种检测蛋白同化激素的量子点标记免疫层析试纸条及其制备方法，ZL201610819591.4.
6. 王俊平，王硕，生威. 一种抗除草剂莎稗磷的特异性抗体，ZL201110326286.9.
7. 王硕，王俊平，生威，王津. 重金属镉抗体及其在中药中镉残留检测的应用，ZL201110325898.6.
8. 王硕，张燕，王俊平，生威，徐欣. 一种抗除草剂伏草隆的特异性抗体，ZL201210425571.0.
可转化成果：
1. 食品小分子危害物抗原、抗体
2. 食品安全快速检测试剂盒及试纸条
联系方式：
通信地址：天津市经济技术开发区第十三大街29号
邮政编码：300457
电 话：022-60912483
E-mail ：shengwei@tust.edu.cn
