Yifulou Building, College of Food Engineering & Biotechnology, Tianjin University of Science and Technology, TEDA, Tianjin, 300457, China
Prof. Yaqing Liu received her BSc in 1998 and PhD in 2006 from Chengdu University of Sciences and Technology and Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, respectively. From 2007 to 2010, Dr. Liu worked as a postdoctoral fellow in Peter Grünberg Institute (PGI-8), Forschungszentrum Jülich, Germany. She joined Changchun Institute of Applied Chemistry, Chinese Academy of Sciences in 2010. Prof. Liu has worked at Tianjin University of Science and Technology since 2015.
The research main involves two fields. One is the food safety detection. Another is rapid and accurate detection biomarkers for early warning of serious diseases. The investigation focuses on the molecular recognition mechanism between aptamer and target to provide theoretical foundation for the development of novel strategy for rapid testing. The research covers the synthesis of bio-nanomaterials, bioimaging, fabrication of molecular devices and molecular logic gates and their applications in bioanalytical fields. The aim is to develop novel approaches and technologies for rapid and accurate detection strategy with high throughput, sensitivity and selectivity. Prof. Liu has over 50 publications in international journals, such as ACS Nano, Angew. Chem. Int. Ed., NPG Asia Mater., Adv. Sci., Chem. Sci.,Anal. Chem. etc. Prof. Liu is principle investigator of eight projects including the National Natural Science Foundation of China, State Key Instrument Developing Special Project of Ministry of Science and Technology of China, the Instrument Developing Project of the Chinese Academy of Sciences, and so on.
Honors & Awards
Prof. Liu is awarded as Distinguished Professor (Tianjin), Young and middle-aged innovative and leading talents (Tianjin), the First Level Innovative Talents of “131” Talent Project (Tianjin), member of Council of Foodborn Microbiology Detection Technology Association (China), member of Expert Committee of Chinese food Newspaper and Association of Chinese Food Colleges.
1.Modern Instrument analysis for graduate student
2. Food Nutrition and Safety for undergraduate students
1.Hailong Li, Wei Hong, Shaojun Dong, Yaqing Liu*, and Erkang Wang* A resettable and reprogrammable DNA-based security system to identify multiple users with hierarchy. ACS Nano 2014, 8, 2796-2803.
2.Yaqing Liu, Bernhard Wolfrum, Martin Hueske, Andreas Offenhaeusser, Erkang Wang, Dirk. Mayer*, Transistor functions based on electrochemical rectification. Angew. Chem. Int. Ed. 2013, 52, 4029-4032.
3.Yaqing Liu, Andreas Offenhaeusser, Dirk Mayer, An Electrochemically transduced XOR logic gate on molecular level. Angew. Chem. Int. Ed. 2010, 49, 2595-2598.
4.Hailong Li , Shaojun Guo , Qinghui Liu , Lidong Qin , Shaojun Dong , Yaqing Liu* , and Erkang Wang*, Implementation of Arithmetic Functions on a Simple and Universal Molecular Beacon Platform. Adv. Sci. 2015, 2, 1500054
5.Shanling Xu, Hailong Li, Yuqing Miao, Yaqing Liu* and Erkang Wang*. Implementation of half adder and half subtractor with a simple and universal DNA-based platform. NPG Asia Materials 2013, 5, e76.
6.Daoqing Fan, Kun Wang, Jinbo Zhu, Yong Xia, Yanchao Han, Yaqing Liu* and Erkang Wang*. DNA-based visual majority logic gate with one-vote veto function. Chemical Science 2015, 6, 1973-1978
7.Xiaodong Lin,Yaqing Liu,*Jiankang Deng,Yanlong Lyu,Pengcheng Qian,Yunfei Liand Shuo Wang, Multiple advanced logic gates made of DNA-Ag nanocluster and the application for intelligent detection of pathogenic bacterial genes. Chemical Science2018, 9, 1774-1781
8.Daoqing Fan,Jinbo Zhu, Yaqing Liu*, Erkang Wang and Shaojun Dong*, Label-free and enzyme-free platform for the construction of advanced DNA logic devices based on the assembly of graphene oxide and DNA-templated AgNCs. Nanoscale2016, 8, 3834-3840
9.Chunyang Zhou, Dali Liu, Changtong Wu, Yaqing Liu* and Erkang Wang，Integration of DNA and Graphene Oxide for the Construction of Various Advanced Logic Circuits. Nanoscale 2016, 8, 17524-17531.
10.Xiaodong Lin, Yaqing Liu*, Zhanhui Tao, Jinting Gao, Jiankang Deng, Ting Guo, Jinjin Yin, Shuo Wang*Nanozyme-based bio-barcode assay for high sensitive and logic-controlled specific detection of multiple DNAs. Biosens. Bioelectron. 2017, 94, 471-477.
11.Kun Wang, D. Fan, Yaqing Liu* and Erkang Wang*, Highly sensitive and specific colorimetric detection of cancer cells via dual-aptamer target binding strategy Biosens. Bioelectron. 2015, 73, 1-6.
12.Hailong Li, Jiyang Liu, Youxing Fang, Yinan Qina, Shanling Xu, Yaqing Liu*, Erkang Wang*, G-quadruplex-based ultrasensitive and selective detection of histidine and cysteine. Biosens. Bioelectron.2013, 41, 563-568.
13.Jiyang Liu, Yinan Qin, Dan Li, Tianshu Wang, Yaqing Liu*, Jin Wang, Erkang Wang*, Highly sensitive and selective detection of cancer cell with a label-free electrochemical cytosensor. Biosens. Bioelectron. 2013, 41, 436-441.
14.Kun Wang, Daoqing Fan, Yaqing Liu*, Shaojun Dong*, Cascaded multiple amplification strategy for ultrasensitive detection of HIV/HCV virus DNA Biosens. Bioelectron.2016, 87, 116-121
15.Yaqing Liu, Andreas Offenhaeusser, Dirk Mayer*, Rectified tunneling current response of bio-functionalized metal-bridge-metal junctions. Biosens. Bioelectron. 2010, 25, 1173-1178.
16.Jiyang Liu, Shaojun Guo, Lei Han, Tianshu Wang, Wei Hong, Yaqing Liu*, Erkang Wang*, Synthesis of phospholipid monolayer membrane functionalized graphene for drug delivery. J. Mater. Chem.2012, 22, 20634-20640.
17.Wei Hong, Yaqing Liu*, Jin Wang, Erkang Wang*,A new kind of highly active hollow flower-like NiPdPt nanoparticles supported by multiwalled-carbon nanotubes toward ethanol electrooxidation. Journal of Power Sources2013, 241, 751-755.
18.Changtong Wu, Daoqing Fan, Chunyang Zhou,Yaqing Liu*, Erkang Wang, A colorimetric strategy for highly sensitive and selective simultaneous detection of histidine and cysteine based on G-quadruplex-Cu (II) metalloenzyme, Anal. Chem. 2016, 88, 2899-2903
19.Jiankang Deng, Zhanhui Tao, Yaqing Liu*, Xiaodong Lin, Pengcheng Qian, Yanlong Lyu, Yunfei Li, Kejing Fu, and Shuo Wang, A target-induced logically reversible logic gate for intelligent and rapid detection of pathogenic bacterial genesChem. Commun. 2018, DOI: 10.1039/C8CC00178B
20.Chunyang Zhou, Kun Wang, Daoqing Fan, Changtong Wu, Dali Liu, Yaqing Liu* and Erkang Wang*, An enzyme-free and DNA-based Feynman gate for logically reversible operation. Chem. Commun. 2015, 51, 10284-10286.
21.Changtong Wu, Kun Wang,Daoqing Fan,Chunyang Zhou,Yaqing Liu,* and Erkang Wang* Enzyme-free and DNA-based multiplexer and demultiplexer Chem. Commun. 2015, 51, 15940-15943
22.Kun Wang, Jiangtao Ren, Daoqing Fan, Yaqing Liu* and Erkang Wang*, Integration of graphene oxide and DNA as a universal platform for multiple arithmetic logic units. Chem. Commun. 2014, 50, 14390-14393.
23.Hailong Li, Jiangtao Ren, Yaqing Liu*, and Erkang Wang*, Application of DNA machine in amplified DNA detection. Chem. Commun. 2014, 50, 704-706.
24.Daoqing Fan, Changtong Wu，Kun Wang, Xiaoxiao Gu, Yaqing Liu* and Erkang Wang*, Polydopamine nanosphere based highly sensitive and selective aptamer cytosensor with Enzyme amplification, Chem. Commun. 2016, 52, 406-409.
25.Yaqing Liu*, Jiangtao Ren, Yinan Qin, Jing Li, Jiyang Liu and Erkang Wang*, An aptamer-based keypad lock system. Chem. Commun. 2012, 48, 802-804.
26.Hailong Li, Dan Li, Jiyang Liu, Yinan Qin, Jiangtao Ren, Shanling Xu, Yaqing Liu*, Dirk Mayer* and Erkang Wang*, Electrochemical current rectifier as a highly sensitive and selective cytosensor for cancer cell detection. Chem. Commun. 2012, 48, 2594-2596.
27.Yinan Qin, Lei Xu, Jiangtao Ren, Yaqing Liu* and Erkang Wang*, Redox mediated electron transfer behaviors at azobenzene functionalized Electrode. Chem. Commun. 2011, 47, 8232-8234.
28.Ting Guo, Xiaodong Lin, Yaqing Liu,* Jiankang Deng, Pengcheng Qian, Yanlong Lyu, Ziying Zhang, ShuoWang*, Target-induced DNA machine amplification strategy for high sensitive and selective detection of biotoxin. Sensors & Actuators: B. Chemical2018, 262, 619-624
29.Jinting Gao, Yaqing Liu*, Xiaodong Lin, Jiankang Deng, Jinjin Yin, Shuo Wang*, Implementation of cascade logic gates and majority logic gate on a simple and universal molecular platform. Sci. Rep. 2017, 7, 14014
30.Jinjin Yin, Yaqing Liu,*Shuo Wang,∗ Jiankang Deng, Xiaodong Lin, Jinting Gao, Engineering a universal and label-free evaluation method for mycotoxins detection based on strand displacement amplification and G-quadruplex signal amplification. Sensors and Actuators B 2018, 256, 573-579
31.Jinting Gao, Jinjin Yin, Zhanhui Tao, Yaqing Liu,* Xiaodong Lin, Jiankang Deng, and Shuo Wang*, An ultrasensitive fluorescence sensor for Cu2+ specific detection in drinking water with simple operation. ACS Omega 2018, 3 (3), 3045-3050.
33.Shanling Xu, Jiyang Liu, Tianshu Wang, Hailong Li, Yuqing Miao, Yaqing Liu*, Jin Wang and Erkang Wang*, A simple and rapid electrochemical strategy for non-invasive, sensitive and specific detection of cancerous Cell. Talanta 2013, 104, 122-127.
35.Kun Wang, Zhanhui Tao, Lei Xu*, Yaqing Liu*, Investigation and Development of Functionalized Aptamer-based Biosensor. Chin J Anal Chem 2014, 41, 298-304.
36.Wei Hong, Yan Du, Tianshu Wang, Jiyang Liu, Yaqing Liu*, Jin Wang, and Erkang Wang*, A DNA based and electrochemically transduced keypad lock system with reset function. Chem. Eur. J. 2012, 18, 14939-14942.
37.Jiyang Liu, Lei Han, Tianshu Wang, Wei Hong, Yaqing Liu*, Erkang Wang*, Enzyme Immobilization and Direct Electrochemistry Based on A Novel Matrix of Phospholipid Monolayer Functionalized Graphene. Chem. Asian J. 2012, 7, 2824-2829.
38.Yinan Qin, JiYang Liu, Dan Li, Lei Xu, Yaqing Liu*, Erkang Wang*, Biocompatible conductive architecture with surface-confined probe for non-invasive electrochemical cytosensing. Electrochem. Commun. 2012, 18, 81-84.
39.Jiyang Liu, Shaojun Guo, Lei Han, Wen Ren, Yaqing Liu*, Erkang Wang*, Multiple pH-responsive graphene composites by non-covalent modification with chitosan. Talanta 2012, 101, 151-156.
40.Yaqing Liu, Erkang Wang and Shaojun Dong*, Rectification behaviors based on redox-active molecular systems. Electrochem. Commun. 2011, 13, 906-908.
41.Yaqing Liu, Andreas Offenhaeusser, Dirk Mayer, Electrochemical current rectification at Bio-Functionalized modified electrode. Bioelectrochemistry 2010, 77, 89-93.
42.Yaqing Liu, Menglong Yang, Zhikun Zheng, Bailin Zhang, Tailoring the electrochemical property of SAM of 16-mercaptohexadecanoic acid on gold (111) electrode with covalently coupling ethylene diamine. Electrochem. Commun.2005, 7, 344-348.
43.Yaqing Liu, Menglong Yang, Zhikun Zheng, Bailin Zhang, In-situ synthesis of Pt nanoparticles in hyperbranched thin film for electrocatalytic reduction of dioxygen. Electrochimica Acta 2005, 51, 605-610.
44.Yaqing Liu, Andreas Offenhaeusser, Dirk Mayer*, Molecular rectification in the metal-bridge molecule-metal junction.Phys Status Solidi A2010, 207, 891-897.
45.Yonghai Song, Yaqing Liu, Menglong Yang, Bailin Zhang, Zhuang Li, Diluting thiol-derivatized oligonucleotide monolayers on Au (111) by mercaptohexanol replacement reaction. Appl. Surf. Sci. 2006, 252, 5693-5699.
46.Menglong Yang, Zhikun Zheng, Yaqing Liu, Bailin Zhang, Scanned probe oxidation on an octadecyl-terminated silicon (111) surface with an atomic force microscope:Kinetic investigations in line patterning. Nanotechnology 2006, 17, 330-337.
47.Menglong Yang, Zhikun Zheng, Yaqing Liu, Bailin Zhang, Kinetics of Atomic Force Microscope-Based Local Anodization Oxidation on Octadecylated Silicon (111) Surface. J. Phys. Chem. B 2006, 110, 10365-10373.
48.Zhikun Zheng, Menglong Yang, Yaqing Liu, Bailin Zhang, Direct Patterning of Negative Nanostructures on Self-assembled Monolayers of 16-mercaptohexadecanoic acid on Au(111) Substrate via Dip-pen Nanolithography. Nanotechnology 2006, 17, 5378-5386.
49.Yuanhong Xu, Yaqing Liu, Jinbo Zhu, Erkang Wang, Discovered triethylamine as impurity in synthetic DNAs for and by electrochemiluminescence techniques. Talanta 2013, 116, 308-314.
50.Zhixue Zhou, Yaqing Liu and Shaojun Dong, DNA-Templated Ag Nanoclusters as Signal Transducer for Label-Free and Resettable Keypad Lock. Chem. Commun. 2013, 49, 3107-3109.
51.Zhanhui Tao, Yinan Qin, Yaqing Liu, Lei Xu, and Erkang Wang, Molecular Switches and Multiple Logic Gates Based on 4-(2-Pyridylazo)resorcinol. Chin. J. Chem. 2013, 31, 721-725.
52.Yuanhong Xu, Yanchao Han, Wenling Gu, Yong Xia, Yaqing Liu, Erkang Wang, New Design for Detection Cell Applied in Magnetic Particle-based Electrochemiluminescence Assays. Electroanalysis 2014, 26, 2563-2566..
53.Lihua Jin, Youxing Fang, Li Shang, Yaqing Liu, Jing Li, Li Wang, Peng Hu and Shaojun Dong, Gold nanocluster-based electrochemically controlled fluorescence switch surface with prussian blue as the electrical signal receptor. Chem. Commun. 2013, 49, 243-245.