Yifulou Building, College of Food Engineering & Biotechnology, Tianjin University of Science and Technology, TEDA, Tianjin, 300457, China
email:
dcheng@tust.edu.cn
phone:
+86 022-60912421
Biography
Dr. Dai Cheng is a Lecturer of the college of Food Engineering and Biotechnology, Tianjin University of Science and Technology. Dr. Cheng completed Bachelor Degrees from Tianjin University of Science and Technology at 2009. Dr. Cheng received his doctoral degree from China Agricultural University at 2014. On the completion of his Ph.D, Dr. Cheng is employed by Tianjin University of Science & Technology as a professor. He published over 20 scientific papers, and served as a peer reviewers for 3 international journals, such as Food Chemistry.
Research Interests
Heavy metal (Cd, Al, Pb, As) pollution is widely distributed in the environment. It has been well known as a neurotoxicant, and important chemical contaminants in food. Heavy metal has been reported to alter the blood–brain barrier; as a result of which it can cause formation of ROS and result in nerve cell damage. With the increasing number of heavy metal exposed people, prevention and control of heavy metal biotoxicity by daily dietary adjustment has become extremely urgent. The mechanisms underlying heavy metal exposure are still controversial. The present study investigated the mechanism of biotoxicity after heavy metal exposure on rat and the potential protective effect of polyphenol extract against heavy metal -induced biotoxicity. Based on the mechanism of the antagonistic effects of CA on dietary Al, the expected results would provide theoretic evidence and reference for prevention and control of Al-induced hazard by daily dietary adjustment.
Recent Publications
[1] Cheng Dai, Wang Xiaomei, Xi Yu, Cao JianKang, Jiang WeiBo.Identification of the Al-binding proteins that account for aluminum neurotoxicity and transport in vivo.Toxicology Research, 2018, 7: 127-135.
[2] Cheng Dai, Wan Zhaodong, Zhang Xinyu, et al., Dietary Chlorella vulgaris Ameliorates Altered Immunomodulatory Functions in Cyclophosphamide-Induced Immunosuppressive Mice.Nutrients, 2017, 9: 708-721.
[3] Cheng Dai, Zhang Xinyu, Li Xiang, et al., Protective and prophylactic effects of chlorogenic acid on aluminuminduced acute hepatotoxicity and hematotoxicity in mice.Chemico-Biological Interactions, 2017 273:125-132.
[4] Cheng Dai, Wang Ruhua, Wang Chunling, Hou Lihua. Mung bean (Phaseolus radiatus L.) polyphenol extract attenuates aluminum-induced cardiotoxicity through an ROS-triggered Ca2+/JNK/NF-kappaB signaling pathway in rats. Food & Function, 2017,8:851-859.
[5] Cheng Dai, Zhang Xinyu, Li Xiang, Hou Lihua,Wang Chunling. Determination of Aluminum in Edible Jellyfish Using Chrome Azurol S with Spot Test on Filter Paper, Anal Sci, 2017,33:185-189
[6] Cheng Dai, Zhang Xinyu,Meng Meng,Han Lirong,Li Caijiao,Hou Lihua,Qi Wentao,Wang Chunling. Inhibitory effect on HT-29 colon cancer cells of a water-soluble polysaccharide obtained from highland barley. International Journal of Biological Macromolecules. 2016, 92:88-95
[7] Cheng Dai, Zhang Xinyu, Meng Meng, Han Lirong, Li Zheng, Hou Lihua, Qi Wentao, Wang Chunling. The protective effect of a buckwheat-enriched diet on renal injury in high salt-induced hypertension in rats. Food & Function, 2016.
8.10,7（8）：3548~3554
[8] Cheng Dai, Meng Meng, Zhang Xinyu, Wang Chunling, An Anti-Tumor Peptide from Musca domestica Pupae (MATP)Induces Apoptosis in Human Liver Cancer Cells HepG2 CellsThrough a ROS-JNK Pathway,International Journal of Peptide Research and Therapeutics. 2016, 23: 101-109
[10] Cheng Dai, Zhu ChunQiu, Wang CunTang, Xu HuiLin, Cao JianKang, Jiang WeiBo. Hepatoprotective effect of apple polyphenol extract against aluminum-induced liver damage in rat, Canadian journal of physiology andpharmacology. 2013, 2014:109-116.
[11] Cheng Dai, Zhu ChunQiu, Cao JianKang, Jiang WeiBo. The protective effects of polyphenols from jujube peel (Ziziphus Jujube Mill) on isoproterenol-induced myocardial ischemia and aluminum-induced oxidative damage in rats. Food and Chemical Toxicology.2012, 50: 1302-1308.
Honors & Awards
üThe third level of “131” Innovative Personnel Training Project from Tianjin City
